The starting structure allows exploration of the structural neighbors of that structure via mutations.
For example, the starting sequences with distinct
tree structures are 70S (chain F)
(80-nt), tRNA (81-nt), P5abc domain of group I intron (56-nt), GTP-binding aptamer (69-nt), modified P5abc domain
(51-nt) and modified GTP-binding aptamer (54-nt). |
We use 30 starting sequences classified by the shape, length range, and function as shown below: |